OLIGOARTIKULARNI JUVENILNI IDIOPATSKI ARTRITIS: PRAVOVREMENA DIJAGNOZA I TERAPIJA U CILJU PREVENCIJE HRONIČNIH OŠTEĆENJA ZGLOBOVA
DOI:
https://doi.org/10.46793/PP240127010LKljučne reči:
juvenilni idiopatski artritis, oligoartikularni artritis, terapijaApstrakt
Oligoartikularni podtip juvenilnog idiopatskog artritisa (JIA) klinički definiše prisustvo artritisa u manje od pet zglobova tokom prvih šest meseci trajanja bolesti. Ako pojava artritisa ostane lokalizovana na manje od pet zglobova tokom celog perioda trajanja bolesti, onda govorimo o trajnom (perzistentnom) oligoartritisu. Ukoliko se u toku 6 meseci od pojave prvih zglobnih tegoba artritis proširi na 5 i više zglobova onda govorimo o esktendiranoj, proširenoj formi oligoartritisa, koji tokom vremena ima isti tok bolesti kao RF negativni poliartritis. Poslednjih decenija nova saznanja o etiopatogenezi JIA i napredak genetskog inženjeringa su omogućili razvoj i primenu novih terapijskih algoritama kod obolelih od JIA što je svakako promenilo tok, prognozu i ishod bolesti kod ovih pacijenata. Savremeni koncept lečenja ima za cilj da obezbedi dobar kvalitet života ovim pacijentima, da se aktivnost bolesti dovede pod kontrolu, da umanji subjektivne tegobe, omogući normalan rast i razvoj dece, očuva funkcionalnost zglobova i prevenira pojavu deformiteta, nastanak invalidnosti i radne nesposobnosti. Savremeni koncept lečenja JIA teži indivudualizaciji terapijskog pristupa svakom bolesniku. U poređenju sa ostalim podtipovima JIA, oligoartikularna forma ima najbolju prognozu, posebno ukoliko govorimo o perzistentnom podtipu oligoartritisa.
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