PREPOZNAVANJE EPILEPTIČNIH NAPADA KOD DJECE ŠKOLSKOG UZRASTA SA PRETHODNO DIJAGNOSTIKOVANIM POREMEĆAJEM IZ DOMENA PSIHOPATOLOGIJE– PRIKAZI SLUČAJA
Ključne reči:
epilepsija, deca, psihopatologijaApstrakt
Djeca školskog uzrasta sa prethodno dijagnostikovanim poremećajem iz domena psihopatologije, su zbog česte somatizacije zahtjevni pacijenti u svakodnevnoj pedijatrijskoj praksi. Takođe, simptomi poremećaja ponašanja i pažnje, anksioznosti i depresije, mogu maskirati kliničku sliku epileptičkih napada. Školski uzrast je karakterističan i za pojavu epileptičkih sindroma, koji imaju odličnu prognozu i odgovor na antiepileptičku terapiju ukoliko se na vrijeme prepoznaju. U suprotnom, epileptički napadi mogu doprinjeti dodatnom pogoršavanju simptoma psihopatologije. Predstavljena su dva prikaza slučaja, pacijent sa novodijagnostikovanom dječjom apsansnom epilepsijom i sa prethodno dijagnostikovanim poremećajem hipektivnosti i drugi pacijent sa novodijagnostikovanom juvenilnom miokloničnom epilepsijom sa prethodno dijagnostikovanom generalizovanim anksioznim poremećajem. Pedijatrijski pacijenti koji ispoljavaju simptome koji mogu ići u prilog epileptičnom napadu, a pri tom imaju dijagnostikovan poremećaj iz domena psihopatologije, trebaju biti upućeni neuro-pedjatru - epileptologu, radi eventualnog postavljanja dijagnoze epilepsije kao čestog komorbiditeta navedenih poremećaja.
Reference
Falco-Walter J. Epilepsy-Definition, Classification, Pathophysiology, and Epidemiology. Semin Neurol. 2020;40(6):617-623. doi:10.1055/s-0040-1718719
Camfield P, Camfield C. Incidence, prevalence and aetiology of seizures and epilepsy in children. Epileptic Disord. 2015;17(2):117-123. doi:10.1684/epd.2015.0736
Specchio N, Wirrell EC, Scheffer IE, et al. International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022;63(6):1398-1442. doi:10.1111/epi.17241
Stafstrom CE, Carmant L. Seizures and epilepsy: an overview for neuroscientists. Cold Spring Harb Perspect Med. 2015;5(6): a022426. Published 2015 Jun 1. doi:10.1101/cshperspect. a022426
Fisher RS. The New Classification of Seizures by the International League Against Epilepsy 2017. Curr Neurol Neurosci Rep. 2017;17(6):48. doi:10.1007/s11910-017-0758-6
Berg AT. Epilepsy, cognition, and behavior: The clinical picture. Epilepsia. 2011;52 Suppl 1(Suppl 1):7-12. doi:10.1111/j.1528-1167.2010. 02905.x
Dagar A, Falcone T. Psychiatric Comorbidities in Pediatric Epilepsy. Curr Psychiatry Rep. 2020;22(12):77. Published 2020 Oct 31. doi:10.1007/s11920-020-01195-8
Oguz A, Kurul S, Dirik E. Relationship of epilepsy-related factors to anxiety and depression scores in epileptic children. J Child Neurol. 2002;17(1):37-40. doi:10.1177/088307380201700109
Otero S. Psychopathology and psychological adjustment in children and adolescents with epilepsy. World J Pediatr. 2009;5(1):12-17. doi:10.1007/s12519-009-0002-9
Chen B, Detyniecki K, Choi H, et al. Psychiatric and behavioral side effects of anti-epileptic drugs in adolescents and children with epilepsy. Eur J Paediatr Neurol. 2017;21(3):441-449. doi: 10.1016/j.ejpn.2017.02.003
Baykan B, Wolf P. Juvenile myoclonic epilepsy as a spectrum disorder: A focused review. Seizure. 2017; 49:36-41. doi: 10.1016/j.seizure.2017.05.011
Kessler SK, McGinnis E. A Practical Guide to Treatment of Childhood Absence Epilepsy. Paediatr Drugs. 2019;21(1):15-24. doi:10.1007/s40272-019-00325-x
Albuja AC, Khan GQ. Absence Seizure. In: StatPearls. Treasure Island (FL): StatPearls Publishing; October 10, 2022.
Garzon P, Lemelle L, Auvin S. Épilepsie absence de l’enfant : actualités diagnostiques et thérapeutiques [Childhood absence epilepsy: An update]. Arch Pediatr. 2016;23(11):1176-1183. doi: 10.1016/j.arcped.2016.08.005
Amrutkar C, Riel-Romero RM. Juvenile Myoclonic Epilepsy. In: StatPearls. Treasure Island (FL): StatPearls Publishing; February 2, 2023.
Xu L, Guo D, Liu YY, Qiao DD, Ye JY, Xue R. Juvenile myoclonic epilepsy and sleep. Epilepsy Behav. 2018; 80:326-330. doi: 10.1016/j.yebeh.2017.11.008
Syvertsen M, Selmer K, Enger U, et al. Psychosocial complications in juvenile myoclonic epilepsy. Epilepsy Behav. 2019; 90:122-128. doi: 10.1016/j.yebeh.2018.11.022
Austin JK, Harezlak J, Dunn DW, Huster GA, Rose DF, Ambrosius WT. Behavior problems in children before first recognized seizures. Pediatrics. 2001;107(1):115-122. doi:10.1542/peds.107.1.115
Rogač Ž, Stevanović D, Bečanović S, et al. Cognitive profile, psychopathological symptoms, and quality of life in newly diagnosed pediatric epilepsy: A six-month, naturalistic follow-up study [published online ahead of print, 2021 Dec 18]. Epilepsy Res. 2021; 179:106844. doi: 10.1016/j.eplepsyres.2021.106844
Tian Y, Dong B, Ma J, Zhou S, Zhou N, Wang K. Attention networks in children with idiopathic generalized epilepsy. Epilepsy Behav. 2010;19(3):513-517. doi: 10.1016/j.yebeh.2010.07.003
