BRONHOPULMONALNA DISPLAZIJA: TRETMAN I PREVENCIJA
DOI:
https://doi.org/10.46793/PP160813002CKljučne reči:
bronhpulmonalna displazija, prevremeno rodjenje, pregled literatureApstrakt
Bronhopulmonalna displazija (BPD) opisana je prvi put 1967. godine. Tadašnja definicija BPD zasnivala se na kliničkim i radiografskim znacima plućne bolesti kod prevremeno rodjene dece, koja su bila na mehaničkoj ventilaciji sa pozitivnim pritiskom i dugotrajno na terapiji kiseonikom. U današnje vreme, BPD se karakteriše zastojem u razvoju alveolarnih i vaskularnih struktura kod prevremeno rodjene dece. BPD se javlja u 1,5% sve novorodjene dece. Incidecna BPD se povećava u skladu sa sve većim preživljavanjem prevremeno rodjene dece, a posebno dece sa vrlo malom porodjajnom težinom, koja su lečena i oporavila se od respiratornog distres sindroma. Ovaj rad je pregled savremene literature, uključujući studije na životinjama, u humanoj populaciji, randomizovane kontrolisane studije, meta analize i sistematski pregled PubMed podataka.
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