THE CONCEPT OF SPLEEN FUNCTION PRESERVATION IN PREVENTION OF POSTSPLENECTOMY SEPSIS
DOI:
https://doi.org/10.46793/PP170218012JKeywords:
postsplenectomy sepsis, nonoperative treatment, minimal invasive surgery, childrenAbstract
Introduction: The spleen is a blood organ whose rupture can cause serious life-threatening bleeding. For a long time period surgery of the spleen was practically reduced to the splenectomy. Postsplenectomy sepsis is the most serious complication of splenectomy.
Objective: The goal is to present and analyse practical use of new concept in children, the preservation of the spleen function, in order to prevent the occurrence of postsplenectomy sepsis.
Methods: We analyzed 71 patients with splenic trauma who were treated at the Clinic of Pediatric Surgery in Novi Sad during the period of 1990-2002, and then followed up till the end of 2016. A control group of 32 patients was formed as retrospective, and a study group of 39 patients as prospective study. Separated key criteria for the therapeutic decision and treatment algorithm for the splenic trauma were proposed. In this paper, the new minimally invasive surgery was presented as well.
Results: Non-operative treatment in the control group was applied in 7 patients, operative preservation of the spleen in 11, and splenectomy in 14 patients. In the study group, non-operative treatment was applied in 28 patients, operative spleen preservation in 8, and splenectomy only in 3 patients. Non-operative treatment was administered to 71.79% of patients in the study group and to 21.88% of patients of the control group. The new concept of preserving the spleen’s function has enabled in saving the organ in 92,18% of cases.
Conclusion: The priority in preserving the function of the spleen is possible by applying nonoperative treatments and/or operative preservation of the spleen. The introduction of minimally invasive surgery opened a new field within the surgical methods. Bearing in mind that the risk of fatal postsplenectomy sepsis is lifelong, it is necessary to overcome splenectomy as the dominant procedure in the management of splenic injuries.
References
Jovanović M. Hirurške mogućnosti i značaj prezervacije povređene slezine (Disertacija). Niš, Jugoslavija: Univerzitet u Nišu, Medicinski fakultet, 1999. 121 strana.
Jokić R. Značaj dijagnostičko-terapijskog koncepta hirurškog očuvanja funkcije slezine u dečjem uzrastu (Disertacija). Novi Sad, Univerzitet u Novom Sadu, Medicinski fakultet, 2003. 105 strana.
King H; Shoemaker WC: Splenic studies: Susceptibility to infection after splenectomy performed in infants; Ann Surg 1952; 136:239
Marvin Hsiao, Chethan Sathya, Charles de Mestral, Jacob C. Langer, David Gomez, Avery B. Nathens. Population-based analysis of blunt splenic injury management in children: Operative rate is an informative quality of care indicator. Injury, 2014; Volume 45, Issue 5, Pages 859-863.
Wang X, Wang M, Zhang H, Peng B. Laparoscopic partial splenectomy is safe and effective in patients with focal benign splenic lesion. Surg Endosc. 2014 Dec; 28(12):3273-8. doi: 10.1007/s00464-014-3600-0. Epub 2014 Jun 18.
Shanmuganathan K, Mirvis SE, Sherbourne CD, Chiu WC, Rodriguez A. Hemoperitoneum as the sole indicator of abdominal visceral injuries: a potential limitation of screening abdominal US for trauma. Radiology 1999; 212: 423-430
Nix JA., Constanza M., Daley BJ., Powell MA., Enderson BL.: Outcome of the current management of splenic injuries. J Trauma, Vol.50 (5), May 2001:835-842
Williams RA; Black JJ; Sinow RM; Wilson SE: Computed tomography- assisted management of splenic trauma; Am J Surg 1997 Sep; 174(3): 276-9
Sirlin CB, Casola G, Brown MA. Patterns of fluid accumulation on screening ultrasonography for blunt abdominal trauma: comparison with site of injury. J Ultrasound Med. 2001 Apr. 20(4):351-7.
Hedrick TL, Sawyer RG, Young JS. MRI for the diagnosis of blunt abdominal trauma: a case report. Emerg Radiol. 2005 Jul. 11(5):309-11.
Moore EE, Cogbill TH, Malangoni MA, Jurkovich GJ, Shackford SR, Champion HR, McAninch JW. Organ injury scaling. Surg Clin North Am 1995; 75: 293-303.
Thomsen RW, Schoonen WM, Farkas DK, et al. Risk for hospital contact with infection in patients with splenectomy: a population based cohort study. Ann Intern Med 2009;151:546–55.
Uranüs S, Pfeifer J. Nonoperative management of blunt splenic injury. World J.Surg. 2001;25:1405–1407.
Villalba MR, Howells GA, Lucas RJ, Glover JL. Nonoperative management of the adult ruptured spleen. Arch Surg 1990 July: Vol 125, 836-839
Kraljević VD. Uticaj podvezivanja splenične arterije na histološke promene i imunološku funkciju slezine (Magistarski rad). Novi Sad, Jugoslavija: Univerzitet u Novom Sadu, Medicinski fakultet, 1993. 61 strana.
Shackford SR; Sise MJ; Virgilio RW; Peters RM. Evaluation of splenorrhaphy: a grading system for splenic trauma. J Trauma, 1981; 21: 538-542
Liu DL; Xia S; Xu W; Ye Q: Anatomy of vasculature of 850 spleen specimens and its application in partial splenectomy; Surg; Vol. 119, No. 1, 1996.
Jokić R, Stojanović S, Ilić M, Škorić S. Criteria for operative decision of splenic salvage in pediatric patients with blunt trauma of abdomen. Monduzzi Editore, Bologna- Italy 1997: 11-15
Buntain WL; Gould HR: splenic trauma in children and techniques of splenic salvage; World J Surg; 1985; 9: 398-409
Gaunt W., McCarthy T., Lambert MC et al. Traditional criteria for observation of splenic trauma should be challenged. Am Surg; l999 Jul, Vol. 65, Issue 7
Mellemkjoer L, Olsen JH, Linet MS et al. Cancer risk after splenectomy. Cancer, 1995 Jan, Vol 75, No2: 577-583