COMPARATIVE STUDY OF PROPOMUCIL® FOR ACUTEUPPER RESPIRATORY INFECTIONS IN CHILDREN

Authors

  • Aleksandra Bajec-Opančina Institute for Mother and Child "Dr. Vukan Čupić", Belgrade, Serbia
  • Vladan Šubarević Institute for Mother and Child "Dr. Vukan Čupić", Belgrade, Serbia
  • Katarina Stanković Institute for Mother and Child "Dr. Vukan Čupić", Belgrade, Serbia
  • Mladen Novković Institute for Mother and Child "Dr. Vukan Čupić", Belgrade, Serbia
  • Vladan Đorđević Clinic for Psychiatric Diseases "Dr. Laza Lazarevic" Belgrade, Serbia

DOI:

https://doi.org/10.46793/PP170309014B

Keywords:

acute respiratory infections, children, PropoMucil®.

Abstract

Introduction and objective. Acute respiratory infections are a very common problem faced by children, especially younger children. Symptomatology in the case of a viral infection is non-specific, and the therapy is also symptomatic. Phytotherapy represents a comparison of the pharmacological properties of chemical drugs interact with plants and products from nature. The modern age has brought the modern guidelines for testing plant which was confirmed by the experience of our ancestors in the use of herbs in the treatment and alleviation of symptoms. The aim of this study was to evaluate the efficacy and safety PropoMucil® PropoMucil® syrup and nasal spray in children with respiratory infections.

Methods and patients. The survey was conducted from January to April 2016, the Institute for Mother and Child "Dr. Vukan Cupic" in Belgrade. The research included two groups of children: Group A-children with symptoms of secretory otitis media and gupa B-children with symptoms of inflammation of the nasal mucosa. In both groups of children were recorded at baseline demographic data, duration of symptoms and comorbidities, and the first follow-up examination and recorded symptoms, otoscopic and tympanometry findings - in group A and endoscopic findings, the appearance of secretions and microbiological findings in group B.

Results. Group A of children at follow-up examination had statistically less frequent symptomatology infection, with normalization of otoscopic and tympanometric findings. In group B children to re-examination had statistically less frequent symptomatology of the infection, with normalization of endoscopic findings,  secretion and microbiological findings.

Conclusion. The study contributed to the evaluation of herbal medicine as a treatment of choice in the prevention and treatment of respiratory infections.

References

Institut za javno zdravlje Srbije „Dr Milan Jovanović Batut“. Zdravstveno-statistički godišnjak Republike Srbije - 2015. Beograd, 2016; ISSN 2217-3714 (Online).

World Health Organization. The managment of acute respiratory infections in children - Practical guidelines for outpatient care. World Health Organization, Geneva 1995. ISBN 92 4 154477 5

Katić M, Švab I i suradnici. Obiteljska medicina. Alfa, Zagreb, 2013.

Školnik-Popović V, Jovančević M. Infekcije dušnih puteva i boravak u kolektivu. Medix 2015; 21 (115/116): 126-130.

Gonzales R, Bartlett J, Besser R, Cooper R, Hickner J, Hoffman J, Sande M. Principles of appropriate antibiotics use for treatment of acute respiratory tract infections in adults: Background, specific aims, and methods. Ann Intern Med. 2001; 134(6): 479-486.

Republička stručna komisija za izradu i implementaciju vodiča u kliničkoj praksi Ministarstva zdravlja Republike Srbije. Izbori i upotreba antibiotika u opštoj praksi - Nacionalni vodič za lekare u primarnoj zdravstvenoj zaštiti. Medicinski fakultet Univerzitet u Beogradu, Beograd 2004. ISBN 86-7117-122-1.

Dales RE, Cakmak S, Brand K, Judek S. Respiratory illness in children attending daycare. Pediatr Pulmonol. 2004; 38(1): 64-9.

Nesti MM, Goldbaum M. Infectious diseases and daycare and preschool education. J Pediatr (Rio J). 2007; 83(4): 299-312.

Dahl IL, Grufman M, Hellberg C, Krabbe M. Absenteeism because of illness at daycare centers and in three-family systems. Acta Paediatr Scand. 1991; 80(4): 436-45.

Wald ER, Guerra N, Byers C. Frequency and severity of infections in day care: three-year follow-up.J Pediatr. 1991; 118(4 Pt 1): 509-14.

Almeida C. E, Menezes H. Anti-inflammatory activity of propolis extracts: A review. J. Venom. Anim. Toxins. 2002; 8(2): pp.191-212.

Cheng P.C, Wong G. Honey bee products: prospects in medicine. Bee World, 1992, 77: 8-15.

Krol W, Scheller S, Shani J, Pietz G, Czuba Z. Synergistic effect of ethanolic extract of propolis and antibiotics on the growth of Staphylococcus aureus. Arzneim. Forsch., 1993, 43: 607-9.

Eastwood M.A. Interaction of dietary antioxidants in vivo: how fruit and vegetables prevent disease. Quarterly journal of medicine. 1999; 92: 527–530.

Hollman P.C, Katan M.B. Health effects and bioavailability of dietary flavonols. Free Radical Research. 1999; 31:S75–S80.

E. S. C. O. P. Monographs. "The Scientific Foundation for Herbal Medicinal Products”, ESCOP, the European Scientific Cooperative on Phytotherapy. Argyle house, Gandy Street, UK. Second Edition.2003:32- 35.

Ali Esmail Al-Snafi et al. The Pharmaceutical Importance of Althaea officinalis and Althaea rosea : A Review. Int J Pharm Tech Res. 2013,5(3): 1387-1385.

Fan C, Pacier C, Martirosyan D. Rose hip (Rosa canina L): A functional food perspective. Funct Foods Health Disease. 2014; 4(11):493-509.

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Published

04/28/2017

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Original Articles