COVID 19 IN PREGNANCY

Authors

  • Jelena Trifunović Kubat KBC "Dr Dragisa Misovic", Hospital for Gynecology and Obstetrics, Belgrade, Serbia
  • Predrag Sazdanović Clinical Center Kragujevac, Clinic for Gynecology and Obstetrics, Kragujevac Serbia. Faculty of Medicine, University of Kragujevac, Kragujevac, Serbia
  • Slađana Mihajlović Faculty of Medicine, University of Belgrade, Belgrade, Serbia
  • Ivana Filipović
  • Filip Mošković Gynecology and Obstetrics Clinic "Narodni Front", Belgrade, Serbia

Keywords:

COVID19, pregnancy, newborn

Abstract

Since the new SARS CoV2 virus was first identified in March 2020 and the pandemic has continued to spread globally, the number of infected and pregnant women requiring hospital treatment as well as treatment in intensive care units has increased. COVID19 in pregnancy has been associated with a number of negative maternal, fetal and neonatal outcomes. Physiological changes that occur in pregnancy, primarily at the level of the immune system, are key to a better understanding of COVID19 infection in pregnancy. In order to better understand the ways of virus transmission between pregnant women and their newborns, they are usually divided into intrauterine, intrapartum and postpartum infections. Although vertical transmission has  been thought to be impossible, the virus has been isolated from the fetal side of the placenta.  COVID19 in pregnancy is associated with poor maternal outcomes in terms of preclampsia, hypertension, premature termination of pregnancy, as well as an increased stillbirth rate, especially in underdeveloped and developing countries.Treatment of pregnant women does not differ significantly from therapy in non-pregnant patients, although studies have shown a significantly higher incidence of hospitalization and treatment needs in intensive care units for pregnant women compared to the general population of women with the same demographics and health status. Numerous studies have shown that pregnancy itself poses an increased risk of complications related to COVID19. Vaccines registered so far are the best specific measure for the prevention of COVID19 infection in pregnancy. By protecting pregnant women, we also protect the health of their offspring.

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Published

03/29/2022

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Review Articles